Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Aug 2003
Randomized Controlled Trial Clinical TrialThe effectiveness of intravenous ketamine and lidocaine on peripheral neuropathic pain.
Neuropathic pain is often severe and resistant to pharmacological treatment. The aims of the present study were to assess the analgesic effect of ketamine and lidocaine and to investigate if measurement of different variables of sensibility could be used to identify responders. We also wanted to study if treatment resulted in changes of sensibility. ⋯ Ketamine showed a significant analgesic effect. The clinical usefulness is, however, limited by disturbing side-effects.
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Acta Anaesthesiol Scand · Aug 2003
Randomized Controlled Trial Comparative Study Clinical TrialContinuous spinal anesthesia/analgesia vs. single-shot spinal anesthesia with patient-controlled analgesia for elective hip arthroplasty.
In total hip replacement surgery several anesthesiological techniques can be used. In this study we compared continuous spinal anesthesia (CSA) and postoperative analgesia vs. single-shot spinal anesthesia (SPA) and postoperative patient-controlled intravenous analgesia with morphine (SPA). ⋯ Continuous spinal anesthesia/analgesia is a very practicable method providing better postoperative analgesia and better hemodynamic stability during anesthesia induction than SPA followed by morphine PCA analgesia after total hip replacement surgery.
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Acta Anaesthesiol Scand · Aug 2003
Randomized Controlled Trial Comparative Study Clinical TrialDexamethasone is as effective as ondansetron for the prevention of postoperative nausea and vomiting following breast surgery.
Postoperative nausea and vomiting remain a common problem following breast surgery. This study assesses whether dexamethasone is as effective as ondansetron in the control of postoperative nausea and vomiting (PONV). ⋯ Ondansetron 4 mg or dexamethasone 4 mg are equally effective in the prevention of postoperative nausea and vomiting following breast surgery. Other factors being similar, the difference in cost between these drugs would favor the use of dexamethasone instead of ondansetron when monotherapy against PONV is used.
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Acta Anaesthesiol Scand · Nov 2003
Multicenter StudyCognitive dysfunction after minor surgery in the elderly.
Major surgery is frequently associated with postoperative cognitive dysfunction (POCD) in elderly patients. Type of surgery and hospitalization may be important prognostic factors. The aims of the study were to find the incidence and risk factors for POCD in elderly patients undergoing minor surgery. ⋯ Our finding of less cognitive dysfunction in the first postoperative week in elderly patients undergoing minor surgery on an out-patient basis supports a strategy of avoiding hospitalization of older patients when possible.
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Acta Anaesthesiol Scand · Aug 2003
Randomized Controlled Trial Comparative Study Clinical TrialComparison of different concentrations of levobupivacaine for post-operative epidural analgesia.
The relative effects of the mass, volume and concentration of local anaesthetic solution used for epidural anaesthesia and analgesia are still under debate. Clinical studies have shown discrepancies, probably because of limited consideration of total dose. ⋯ The same dose of levobupivacaine provides an equal quality of analgesia in low or high volume continuous thoracic epidural infusion with reduced haemodynamic instability and nausea in the low volume/high concentration groups.