Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Mar 2015
Randomized Controlled TrialIntravenous lidocaine increases the depth of anaesthesia of propofol for skin incision - a randomised controlled trial.
The anaesthetic potency of intravenous propofol is quantified by its Cp50 value, which is defined as the plasma concentration required to prevent movement response in 50% of patients to surgical stimuli. We hypothesised that, in addition to propofol anaesthesia, an intravenous bolus of lidocaine 1.5 mg/kg will decrease the Cp50 value of propofol during anaesthesia. ⋯ An intravenous bolus injection of 1.5 mg/kg lidocaine 2% caused a significant reduction of the propofol Cp50 value.
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Acta Anaesthesiol Scand · Mar 2015
Randomized Controlled Trial Comparative StudyTotal intravenous general anaesthesia vs. spinal anaesthesia for total hip arthroplasty: a randomised, controlled trial.
The choice of anaesthetic technique for patients undergoing joint arthroplasty is debatable. The hypothesis of this study was that general anaesthesia would generate a more favourable recovery profile than spinal anaesthesia. ⋯ General anaesthesia resulted in a more favourable recovery profile compared with spinal anaesthesia.
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Acta Anaesthesiol Scand · Mar 2015
Online breath analysis of propofol during anesthesia: clinical application of membrane inlet-ion mobility spectrometry.
Breath analysis of propofol is a potential noninvasive method for approximating the plasma propofol concentration. There have been various reported techniques for measuring the exhaled propofol concentration at steady state; however, the propofol concentration undergoes marked changes during clinical anesthesia. Therefore, this study investigated the use of membrane inlet-ion mobility spectrometry (MI-IMS) to monitor exhaled propofol discontinuously and continuously during propofol anesthesia. ⋯ MI-IMS may be a suitable method to predict plasma propofol concentration online during propofol anesthesia. Monitoring exhaled propofol may improve the safety of propofol anesthesia.
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Acta Anaesthesiol Scand · Mar 2015
Randomized Controlled TrialAcute kidney injury with hydroxyethyl starch 130/0.42 in severe sepsis.
We aimed to detail the effects of hydroxyethyl starch (HES) vs. Ringer's on kidney function including the interaction with mortality in post-hoc analyses as resuscitation with HES 130/0.42 increased mortality in the Scandinavian Starch for Severe Sepsis/Septic Shock (6S) trial. ⋯ In patients with severe sepsis, HES appeared to increase the rate of severe AKI and use of RRT within the first 5 days. The increased mortality observed with HES may have been partly mediated through acute kidney impairment.
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Acta Anaesthesiol Scand · Mar 2015
Safety of pediatric continuous interscalene block catheters placed under general anesthesia: a single center's experience.
The use of interscalene catheters is an effective treatment strategy for children and adolescents undergoing shoulder surgery. Although placement of interscalene catheters in the awake child is challenging, some have cautioned against performing regional anesthesia in the patient under general anesthesia. We present a case series of 154 interscalene catheters placed in pediatric patients under general anesthesia and managed in the outpatient setting. ⋯ Interscalene catheter placement under general anesthesia and management on an outpatient basis is feasible in the pediatric population and is associated with a low rate of catheter-related complications.