Acta anaesthesiologica Scandinavica
-
Acta Anaesthesiol Scand · Apr 2017
Observational StudyTime course and reasons for 90-day mortality in fast-track hip and knee arthroplasty.
Post-operative mortality is an important adverse outcome, including in total hip (THA) and knee arthroplasty (TKA). However, whether mortality is due to anaesthetic/surgical complications, surgically induced organ dysfunction or unrelated to surgery is rarely considered. ⋯ Ninety-days mortality was 0.3% in THA and TKA, but only 28 of 44 deaths (64%) were found to be surgery-related. Reporting total mortality rate or cause of death without considerations on surgery induced organ dysfunction, may be insufficient for future aims to reduce post-operative mortality.
-
Acta Anaesthesiol Scand · Apr 2017
Early treatment with isoflurane attenuates left ventricular dysfunction and improves survival in experimental Takotsubo.
Takotsubo syndrome (TS) is an acute cardiac condition, often triggered by critical illness, for which no specific treatment exists. Previously, we showed that isoflurane can prevent experimental TS. The aim of this study was to evaluate the potential treatment effects of isoflurane. Our primary hypothesis was that early treatment with isoflurane attenuates left ventricular akinesia in experimental TS. ⋯ Early treatment with isoflurane attenuates the LV akinesia and improves survival in experimental TS. Isoflurane sedation in patients at risk of developing Takotsubo syndrome could be a subject for future studies.
-
Acta Anaesthesiol Scand · Apr 2017
Randomized Controlled Trial Comparative StudyA comparison of sugammadex and neostigmine for reversal of rocuronium-induced neuromuscular blockade in children.
Sugammadex is designed to be a reversal agent for steroidal muscle relaxants. The current trial was aimed to compare between sugammadex and neostigmine concerning the recovery time from neuromuscular blockade. We hypothesised that sugammadex might have shorter recovery time than neostigmine. ⋯ Sugammadex administration in children resulted in faster recovery and extubation times and lower incidence of adverse events compared with neostigmine.
-
Acta Anaesthesiol Scand · Apr 2017
Randomized Controlled Trial Comparative StudyThe novel video-assisted intubating laryngeal mask Totaltrack compared to the intubating laryngeal mask Fastrach - a controlled randomized manikin study.
The novel Totaltrack combines a supraglottic airway device with video laryngoscopic tracheal intubation. The intubation laryngeal mask Fastrach is an established device without visual control of intubation. We hypothesized that supraglottic ventilation success with Totaltrack would be similar to Fastrach, but intubation would be performed faster due to visual control of the procedure. ⋯ In this manikin-based study the novel Totaltrack did not prove superior to Fastrach despite a similar design. Video laryngoscopic control of supraglottic ventilation and endotracheal intubation was prolonged using the Totaltrack. Clinical trials are mandatory to evaluate the role of the Totaltrack in airway management.