Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Apr 2017
Randomized Controlled Trial Multicenter StudyEffects of fluid restriction on measures of circulatory efficacy in adults with septic shock.
The haemodynamic consequences of fluid resuscitation in septic shock have not been fully elucidated. Therefore, we assessed circulatory effects in the first 24 h of restriction of resuscitation fluid as compared to standard care in intensive care unit (ICU) patients with septic shock. ⋯ We observed no indications of worsening of measures of circulatory efficacy in the first 24 h of restriction of resuscitation fluid as compared with standard care in adults with septic shock who had received initial resuscitation.
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Acta Anaesthesiol Scand · Apr 2017
Randomized Controlled Trial Comparative StudyA comparison of sugammadex and neostigmine for reversal of rocuronium-induced neuromuscular blockade in children.
Sugammadex is designed to be a reversal agent for steroidal muscle relaxants. The current trial was aimed to compare between sugammadex and neostigmine concerning the recovery time from neuromuscular blockade. We hypothesised that sugammadex might have shorter recovery time than neostigmine. ⋯ Sugammadex administration in children resulted in faster recovery and extubation times and lower incidence of adverse events compared with neostigmine.