Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Mar 2019
Randomized Controlled Trial Multicenter StudyIndications for fluid resuscitation in patients with septic shock: Post-hoc analyses of the CLASSIC trial.
Fluid resuscitation is recommended in septic shock, but the specific indications for fluids have not been established. Our aim was to investigate the indications currently used for fluid resuscitation and the effect of fluid on these indications in patients with septic shock admitted to the intensive care unit (ICU). ⋯ In ICU patients with septic shock, low blood pressure, high lactate, and low urinary output were the most frequent indications for fluid. The effects of fluids when given on these indications were less clear, but may dependent on the time course of sepsis resuscitation.