Archives of orthopaedic and trauma surgery
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Arch Orthop Trauma Surg · Dec 2012
Treatment of bone marrow edema syndrome with intravenous ibandronate.
In this pilot study, we investigated the therapeutic efficacy of intravenous Ibandronate compared to pain medication on the outcome of bone marrow edemas (BME) of the knee and talus. ⋯ Intravenous Ibandronate therapy showed significantly better clinical results and BME regression rates on MR-imaging compared to analgesic medication in combination with partial weight bearing in the treatment of BME of the knee and talus and shortens the natural course of the disease.
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Arch Orthop Trauma Surg · Dec 2012
Effects of the grade, stability, chronological classification and being either unilateral or bilateral of the slip on the treatment by in situ single screw fixation of patients with slipped capital femoral epiphysis.
The effects of the grade, stability, chronological classification and being either unilateral or bilateral of the slip on the outcomes of the treatment by in situ single screw fixation of the Slipped capital femoral epiphysis were investigated. ⋯ The outcomes of the treatment by in situ single screw fixation are negatively affected by increase in the grade of slip, instability of the slip and existence of slip at both hips.
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Arch Orthop Trauma Surg · Dec 2012
Percutaneous CT-guided radio-frequency ablation of osteoid osteoma of the foot and ankle.
Percutaneous radiofrequency ablation (RFA) has been considered, in recent years, the standard treatment for osteoid osteoma (OO) of the appendicular skeleton. The variable clinical presentations in the foot and ankle pose problems in diagnosis, localization and thus treatment. The aim of this study was to assess the efficacy of RFA for patients with osteoid osteoma of the foot and ankle. ⋯ CT-guided RFA of foot and ankle osteoid osteoma is a safe and effective procedure, showing similar results for the rest of the appendicular skeleton.
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Arch Orthop Trauma Surg · Dec 2012
Meta Analysis Comparative StudyRecombinant human bone morphogenetic protein-2 versus autogenous iliac crest bone graft for lumbar fusion: a meta-analysis of ten randomized controlled trials.
Recombinant human bone morphogenetic protein-2 (rhBMP-2) as a substitute for iliac crest bone graft (ICBG) has been increasingly widely used in lumbar fusion. It has been proven non-inferior in fusion success and clinical outcomes when compared with ICBG. However, increasingly, some potentially uncommon and serious complications associated with the use of rhBMP-2 have been of great concern to surgeons. The purpose of this study was to determine whether rhBMP-2 could be considered an effective and, more importantly, a relatively safe substitute for ICBG in lumbar fusion. ⋯ RhBMP-2 was superior to the ICBG for achieving fusion success and avoiding reoperation. However, evidence from the Food and Drug Administration document and subsequent independent studies has demonstrated that original, industry-sponsored trials underestimated rhBMP-2-related adverse events. There are still security risks in the use of rhBMP-2.