Journal of nephrology
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Journal of nephrology · Feb 2015
Review Meta AnalysisUrine interleukin-18 in prediction of acute kidney injury: a systemic review and meta-analysis.
Interleukin-18 (IL-18) mediates ischemic acute tubular necrosis; it has been proved as a rapid, reliable, and affordable test marker for the early detection of acute kidney injury (AKI), but its predictive accuracy varies greatly. ⋯ Urine IL-18 holds promise as a biomarker in the prediction of AKI but has only moderate diagnostic value.