Dermatology : international journal for clinical and investigative dermatology
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Dermatology (Basel) · Jan 2004
Randomized Controlled Trial Comparative Study Clinical TrialAn open, randomized, comparative study of oral finasteride and 5% topical minoxidil in male androgenetic alopecia.
Androgenetic alopecia (AGA) is undoubtedly the most common form of hair loss in males. It is a condition which may cause cosmetic and psychosocial problems in androgen-dependent cases. In this open, randomized and comparative study we evaluated the efficacy of oral finasteride and 5% topical minoxidil treatment for 12 months in 65 male patients with mild to severe AGA. ⋯ In this comparative study of systemic finasteride and topical minoxidil, it was concluded that both drugs were effective and safe in the treatment of mild to severe AGA, although oral finasteride treatment was more effective (p < 0.05). Adverse events were not considered important either, and these side effects disappeared as soon as the treatment was stopped.
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Dermatology (Basel) · Jan 2002
Randomized Controlled Trial Comparative Study Clinical TrialSkin disinfection before epidural catheterization: comparative study of povidone-iodine versus chlorhexidine ethanol.
Chlorhexidine is better than povidone-iodine for skin preparation before intravascular device insertion or blood culture collection, but it is not known whether chlorhexidine is superior in reducing the colonization of continuous epidural catheters. ⋯ The effect of 0.5% chlorhexidine ethanol is not different from that of 10% povidone-iodine in reducing catheter colonization associated with short-term epidural catheter placement.
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Dermatology (Basel) · Jan 1996
Randomized Controlled Trial Clinical TrialDouble-blind crossover study of high-dose cetirizine in cholinergic urticaria.
Cholinergic urticaria does not respond well to treatment with conventional antihistamines and is difficult to study because of its highly variable clinical expression which depends on the presence of eliciting factors. ⋯ These data show a high efficacy of cetirizine at twice its normally recommended dose which may be related to the specific antiallergic effects of this newer-generation antihistamine.