Medicina intensiva
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To evaluate if there is an association between obesity and mortality in the Intensive Care Unit (ICU) in adult patients receiving invasive mechanical ventilation. ⋯ No relationship was found between the subgroup of obese adult patients receiving IMV and the mortality variable in the ICU.
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A meta-analysis was performed to assesses the effect of storage age of transfused red blood cells (RBCs) upon clinical outcomes in critically ill adults. ⋯ The transfusion of fresher RBCs compared with older RBCs was not associated to better clinical outcomes in critically ill adults.
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To ascertain the ability of adrenomedullin (ADM) and proadrenomedullin (proADM) to predict mortality in sepsis patients. ⋯ Both ADM and proADM might serve as useful markers for predicting the prognosis of sepsis.
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Review Meta Analysis
Levosimendan in patients with cardiogenic shock complicating myocardial infarction: A meta-analysis.
Cardiac shock is the leading cause of death in patients with acute myocardial infarction. The objective of this systematic review and meta-analysis was to evaluate whether levosimendan, compared to any type of control, is associated with improved clinical outcomes in patients with cardiogenic shock complicating myocardial infarction. ⋯ Levosimendan can improve hemodynamic parameters and cardiac function when compared with a control group, with no evidence of benefit in terms of survival.
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Review Meta Analysis
The effects of prone position ventilation in patients with acute respiratory distress syndrome. A systematic review and metaanalysis.
Prone position ventilation has been shown to improve oxygenation and ventilatory mechanics in patients with acute respiratory distress syndrome. We evaluated whether prone ventilation reduces the risk of mortality in adult patients with acute respiratory distress syndrome versus supine ventilation. ⋯ Prone position ventilation is a safe strategy and reduces mortality in patients with severely impaired oxygenation. It should be started early, for prolonged periods, and should be associated to a protective ventilation strategy.