The American journal of the medical sciences
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Review Case Reports
Diagnostic Challenges and Dilemmas in Tuberculous Meningitis.
Tuberculosis is a global burden with an unacceptably high mortality rate, especially in low- and middle-income countries. We reported the case of 34-year-old Somali female with no significant risk factors who initially presented with headache and blurred vision. The patient subsequently developed altered mental status and significant vision changes. ⋯ Repeated polymerase chain reactions for Mycobacterium tuberculosis from the lumbar drain samples was positive, and the diagnosis of tuberculous meningitis was confirmed. The patient improved after lumbar drain placement and treatment with isoniazid, rifampin, pyrazinamide, ethambutol and steroid tapering. This case illustrated the challenge of diagnosing tuberculous meningitis.
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It has been reported that miR-294 is highly expressed in hepatocellular carcinoma (HCC) tissues and cells. However, the potential role of miR-294 in the pathogenesis of HCC remains unclear. This study aimed to explore the role of miR-294 in HCC and the potential mechanism involved in this process. ⋯ miR-294 is important for the development of HCC in terms of the biological activities of cells, and may be a novel therapeutic target for HCC.
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Letter Case Reports
Staghorn Renal Stone With Magnesium Ammonium Phosphates Crystals.
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Editorial Historical Article
Why Did the Original Jones Criteria Not Emphasize Streptococcal Infection?