Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
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Review Meta Analysis
An umbrella review of effect size, bias, and power across meta-analyses in emergency medicine.
The objective of this study was to conduct an umbrella review of therapeutic studies relevant to emergency medicine, analyzing patterns in effect size, power, and signals of potential bias across an entire field of clinical research. ⋯ Few interventions studied within SRMAs relevant to emergency medicine seem to have strong and unbiased evidence for improving outcomes. The field would benefit from more optimally powered trials.