Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
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Acad Emerg Med
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Multicenter Study
Negative predictive value of acetaminophen concentrations within four hours of ingestion.
The objective was to ascertain whether acetaminophen (APAP) concentrations less than 100 μg/mL obtained between 1 and 4 hours after acute ingestion accurately predict a nontoxic 4-hour concentration. ⋯ An APAP concentration of <100 μg/mL obtained between 1 and 4 hours after ingestion has a high NPV for excluding toxic ingestion. We do not recommend reliance on concentrations obtained between 1 and 4 hours to exclude toxicity, because of a potential false-negative rate of 6.5%.