Croatian medical journal
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Croatian medical journal · Apr 2023
ReviewHematopoietic stem cell transplantation in Zagreb: the first 40 years.
Hematopoietic stem cell transplantation is the most effective treatment for acute leukemia, severe aplastic anemia, and some hereditary hematological disorders. The principal source of stem cells in this procedure are bone marrow and peripheral blood cells. In recent years, the transplantation outcome has significantly improved. ⋯ Improved patient care has decreased toxicity and mortality after treatment. This article gives an overview of the 40-year history of the Zagreb transplant program. It also discusses the use of hematopoietic stem cell transplantation in various hematological disorders, with a special emphasis on the publications by the Zagreb transplant team.
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To assess the incidence and mortality trends of invasive vulvar cancer in Croatia between 2001 and 2019/2020. ⋯ In the studied period, the incidence of invasive vulvar cancer in Croatia was stable. Age-standardized rates (for all-ages, under 60, and over 60 years of age) increased, but the increase did not reach the level of statistical significance. The pattern in younger and older age groups was the same. The mortality rates over the last decade were stable.
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Croatian medical journal · Apr 2023
Meta AnalysisInfection with human cytomegalovirus, Epstein-Barr virus, and high-risk types 16 and 18 of human papillomavirus in EGFR-mutated lung adenocarcinoma.
To assess the frequency of human cytomegalovirus (HCMV), Epstein-Barr virus (EBV), and high-risk types of human papillomavirus (HPV16 and HPV18) infections in lung adenocarcinoma samples. ⋯ HCMV, EBV, and high-risk HPV infections are more frequent in EGFR-mutated lung adenocarcinomas, which indicates a possible viral impact on the etiology of this lung cancer subtype.