Archives of disease in childhood. Fetal and neonatal edition
-
Arch. Dis. Child. Fetal Neonatal Ed. · Mar 2009
Randomized Controlled TrialThe effect of two levels of pressure support ventilation on tidal volume delivery and minute ventilation in preterm infants.
To study the effect of different levels of pressure support ventilation (PSV) on respiratory parameters in preterm infants during the weaning phase of mechanical ventilation. ⋯ Pressure support ventilation increases total minute ventilation and stabilises breathing in proportion to the level of pressure support used. This may be advantageous and provide a useful ventilation strategy for use during weaning stages of mechanical ventilation in preterm infants.
-
Arch. Dis. Child. Fetal Neonatal Ed. · Sep 2008
Randomized Controlled Trial Multicenter StudyMorphine analgesia and gastrointestinal morbidity in preterm infants: secondary results from the NEOPAIN trial.
To investigate the influence of morphine therapy and other factors on the attainment of full enteral feeds and on acquired gastrointestinal pathology in preterm infants. ⋯ Morphine delays the attainment of full enteral feeds, partly by delaying the start of feeding, but does not discernibly increase gastrointestinal complications. The attainment of full feeds is influenced by morphine dose, but other factors seem to be important, including birth weight and neonatal morbidity.
-
Arch. Dis. Child. Fetal Neonatal Ed. · Sep 2008
Randomized Controlled Trial Comparative StudyDoes the monitoring method influence stability of oxygenation in preterm infants? A randomised crossover study of saturation versus transcutaneous monitoring.
Hyperoxia and variable oxygenation are associated with morbidity in preterm infants. The optimal range of oxygen tensions is not known. This study aimed to determine whether care based on transcutaneous oxygen tension (TcPO2) or saturation (SpO2) monitoring is associated with less time spent with high oxygen tension and less variability of oxygenation. ⋯ Within the target ranges studied SpO2 monitoring was associated with significantly more variable oxygenation than TcPO2 monitoring.
-
Arch. Dis. Child. Fetal Neonatal Ed. · Jul 2008
Randomized Controlled TrialPharyngeal pressure value using two continuous positive airway pressure devices.
The aim of the study was to measure the difference between the set continuous positive airway pressure (CPAP) value and the pharyngeal pressure reading during CPAP in premature infants with mild respiratory distress syndrome, using two different devices: hood CPAP and the conventional nasal system. The preliminary results suggest that hood CPAP may produce more stable pharyngeal pressure than the conventional nasal device.
-
Arch. Dis. Child. Fetal Neonatal Ed. · Mar 2008
Randomized Controlled TrialLingual sucrose reduces the pain response to nasogastric tube insertion: a randomised clinical trial.
To determine whether lingual sucrose modifies the pain response to nasogastric tube insertion in preterm infants. ⋯ Nasogastric tube insertion induces a pain response comparable with previously reported responses to heel lance in neonates. Single-dose lingual 24% sucrose is effective in reducing the behavioural and physiological pain response to nasogastric tube insertion in preterm infants and it appears to be safe.