Multiple sclerosis : clinical and laboratory research
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Deep gray matter (DGM) atrophy is common in multiple sclerosis (MS), but no studies have investigated surface-based structure changes over time with respect to healthy controls (HCs). Moreover, the relationship between cognition and the spatio-temporal evolution of DGM atrophy is poorly understood. ⋯ These findings highlight the role of atrophy in the anterior nucleus of the thalamus and its relation to cognitive decline in MS.