Annals of internal medicine

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• Ann. Intern. Med. · Feb 2024

  Gene Therapy Versus Common Care for Eligible Individuals With Sickle Cell Disease in the United States : A Cost-Effectiveness Analysis.

  Sickle cell disease (SCD) and its complications contribute to high rates of morbidity and early mortality and high cost in the United States and African heritage community. ⋯ National Heart, Lung, and Blood Institute.

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• Ann. Intern. Med. · Feb 2024

  Comment

  AABB recommends restrictive RBC transfusions for hospitalized adults and children.

  Carson JL, Stanworth SJ, Guyatt G, et al. Red blood cell transfusion: 2023 AABB international guidelines. JAMA. 2023;330:1892-1902. 37824153.

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• Ann. Intern. Med. · Feb 2024

  Comment

  In persons aged ≥45 y, the mt-sRNA test had 94% sensitivity for colorectal cancer and 46% for advanced adenomas.

  Barnell EK, Wurtzler EM, La Rocca J, et al. Multitarget stool RNA test for colorectal cancer screening. JAMA. 2023;330:1760-1768. 37870871.

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• Ann. Intern. Med. · Feb 2024

  Comment

  In nursing homes, universal decolonization vs. routine care reduced transfers to hospital for infection.

  Miller LG, McKinnell JA, Singh RD, et al. Decolonization in nursing homes to prevent infection and hospitalization. N Engl J Med. 2023;389:1766-1777. 37815935.

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• Ann. Intern. Med. · Feb 2024

  Editorial Comment

  Understanding How Older Adults Use the U.S. Health Care System: From Measurement to Meaning.

  no abstract available

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