Annals of internal medicine
-
Randomized Controlled Trial
Blood Pressure Effect of Traffic-Related Air Pollution : A Crossover Trial of In-Vehicle Filtration.
Ambient air pollution, including traffic-related air pollution (TRAP), increases cardiovascular disease risk, possibly through vascular alterations. Limited information exists about in-vehicle TRAP exposure and vascular changes. ⋯ U.S. Environmental Protection Agency and National Institutes of Health.
-
Randomized Controlled Trial Multicenter Study
Efficacy of Acupuncture for Chronic Spontaneous Urticaria : A Randomized Controlled Trial.
The effectiveness of acupuncture for patients with chronic spontaneous urticaria (CSU), reported in a few small-scale studies, is not convincing. ⋯ The National Key R&D Program of China and the Science and Technology Department of Sichuan Province.
-
Randomized Controlled Trial
Impact of Finerenone-Induced Albuminuria Reduction on Chronic Kidney Disease Outcomes in Type 2 Diabetes : A Mediation Analysis.
In patients with chronic kidney disease (CKD) and type 2 diabetes (T2D), finerenone, a nonsteroidal mineralocorticoid receptor antagonist, reduces cardiovascular and kidney failure outcomes. Finerenone also lowers the urine albumin-to-creatinine ratio (UACR). Whether finerenone-induced change in UACR mediates cardiovascular and kidney failure outcomes is unknown. ⋯ Bayer AG.
-
Comment Randomized Controlled Trial
In low-risk penicillin allergies, direct oral challenge was noninferior to skin testing followed by oral challenge.
Copaescu AM, Vogrin S, James F, et al. Efficacy of a clinical decision rule to enable direct oral challenge in patients with low-risk penicillin allergy: the PALACE randomized clinical trial. JAMA Intern Med. 2023;183:944-952. 37459086.