Annals of surgery
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The purpose of this report is to describe our experience in management of aortoesophageal fistulas (AEF) with special emphasis on the value of in situ aortic allograft replacement. ⋯ Our experience confirms that AEF is a rare but catastrophic disorder. In situ allograft replacement usually in association with subtotal esophagectomy appears to be an excellent salvage modality whenever emergency surgery is feasible.
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To evaluate the influence of modest endotoxemia on postoperative antithrombin deficiency and cholestasis. ⋯ The influence of modest endotoxemia on postoperative antithrombin deficiency and cholestasis was limited, and increased translocational endotoxemia during abdominal surgery may be a physiological phenomenon to trigger off an acute-phase protein response.
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To predict the impact of the aging population on the demand for surgical procedures. ⋯ The aging of the US population will result in significant growth in the demand for surgical services. Surgeons need to develop strategies to manage an increased workload without sacrificing quality of care.
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This study sought to determine whether hypertonic saline (HTS) infusion modulates the host response to bacterial challenge. ⋯ HTS significantly enhances intracellular killing of bacteria while attenuating receptor-mediated activation of proinflammatory cascades.