Annals of surgery
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Comparative Study
Paradoxical effect of IL-18 therapy on the severe and mild Escherichia coli infections in burn-injured mice.
To investigate the effects of IL-18 therapy on severe and mild bacterial infection after burn injury. ⋯ IL-18 therapy can be a potent therapeutic tool against severe bacterial infection in immunocompromised hosts, but careful attention should also be paid to its adverse effects.
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Comment Letter
Are actual standard fluid regimens in major surgery safe?
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Comparative Study
Anastomotic leakage is predictive of diminished survival after potentially curative resection for colorectal cancer.
The aim of this study was to determine whether anastomotic leakage has an independent association with overall survival and cancer-specific survival. ⋯ Apart from its immediate clinical consequences, anastomotic leakage also has an independent negative association with survival.
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Randomized Controlled Trial Comparative Study Clinical Trial
The educational impact of bench model fidelity on the acquisition of technical skill: the use of clinically relevant outcome measures.
To evaluate the impact of bench model fidelity on the acquisition of technical skill using clinically relevant outcome measures. ⋯ Surgical skills training on low-fidelity bench models appears to be as effective as high-fidelity model training for the acquisition of technical skill among novice surgeons.
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Comparative Study
Incomplete cytoreduction in 174 patients with peritoneal carcinomatosis from appendiceal malignancy.
The aim of this study was to analyze the survival of patients with peritoneal dissemination of appendiceal malignancy having incomplete cytoreductive surgery. ⋯ Incomplete cytoreduction plus perioperative intraperitoneal chemotherapy of peritoneal dissemination from appendiceal malignancy results in limited long-term survival. Patients with signet ring histology or lymph node involvement have an especially poor outcome. Repeat cytoreduction and intraperitoneal chemohyperthermia may improve outcome.