Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Feb 2021
Case ReportsAcute Hepatitis-A Virus Infection as a Rare Cause of Hemophagocytic Lymphohistiocytosis.
Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder of the mononuclear phagocytic system, characterised by histiocyte and lymphocyte activation. It can be classified as primary and secondary HLH. ⋯ We describe a case of HLH secondary to acute hepatitis-A virus infection, which was characterised by persistent fever, pancytopenia, splenomegaly, hyperferritinemia, and hemophagocytosis observed in the bone marrow. Key Words: Hemophagocytic lymphohistiocytosis, Hepatitis-A, Mononuclear phagocytes.
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J Coll Physicians Surg Pak · Feb 2021
Case ReportsConcurrent Arterial and Venous Thrombosis in a Patient with Ulcerative Colitis in Remission Phase.
Vascular thrombosis is an unusual yet well-known extra-intestinal complication of ulcerative colitis, usually involving the peripheral veins and occasionally the cerebral veins and the arterial system. We, herein, report a case of a 45-year female with ulcerative colitis in remitting phase presenting with anemia and right lower limb swelling and discoloration due to extensive arterial and venous thrombosis. Early and accurate diagnosis of thrombotic complications is essential to start limb-saving and life-saving therapy. Key Words: Thrombotic, Ulcerative colitis.