Archives of disease in childhood
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Randomized Controlled Trial Multicenter Study
Restricted fluid bolus volume in early septic shock: results of the Fluids in Shock pilot trial.
To determine the feasibility of Fluids in Shock, a randomised controlled trial (RCT) of restricted fluid bolus volume (10 mL/kg) versus recommended practice (20 mL/kg). ⋯ Participants were not as unwell as expected. A larger trial is not feasible in its current design in the UK.
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Multicenter Study
Epidemiology and aetiology of paediatric traumatic cardiac arrest in England and Wales.
To describe the epidemiology and aetiology of paediatric traumatic cardiac arrest (TCA) in England and Wales. ⋯ Survival is possible from the resuscitation of children in TCA, with overall survival comparable to that reported in adults. The highest survival was observed in those with a pre-hospital only TCA, and those who were transported to an MTC. Early identification and aggressive management of paediatric TCA is advocated.
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We sought to measure the diagnostic accuracy of D-dimer in children with suspected pulmonary embolism (PE). ⋯ D-dimer is currently ordered in children for suspected PE in the emergency care setting, mostly in teenagers. The observed lower limit 95% CIs of 89% and 54% for diagnostic sensitivity and the specificity, respectively, suggest if used in patients with low-clinical probability, a normal D-dimer can safely exclude PE in children.
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Multicenter Study Observational Study
Oral injuries and occult harm in children evaluated for abuse.
To determine the frequency of occult trauma in children with oral injury evaluated for physical abuse. ⋯ Children with oral injury are at high risk for additional occult abusive injuries. Infants and mobile preschoolers are at risk. Young children with unexplained oral injury should be evaluated for abuse.
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Multicenter Study Observational Study
Takeaway meal consumption and risk markers for coronary heart disease, type 2 diabetes and obesity in children aged 9-10 years: a cross-sectional study.
To investigate associations between takeaway meal consumption and risk markers for coronary heart disease, type 2 diabetes and obesity risk markers in children. ⋯ More frequent takeaway meal consumption in children was associated with unhealthy dietary nutrient intake patterns and potentially with adverse longer term consequences for obesity and coronary heart disease risk.