British journal of anaesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Flunitrazepam compared with althesin as an induction agent in balanced anaesthesia.
The effects of flunitrazepam and Althesin as anaesthetic induction agents were studied in a double-blind trial in 97 patients undergoing abdominal or gynaecological surgery. There was no difference between the two preparations in respect of the quality of induction. ⋯ Recovery was more rapid from Althesin anaesthesia. A low incidence of nausea was observed in both groups.
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Clinical Trial Controlled Clinical Trial
Spread of extradural analgesia following caudal injection in children. A statistical study.
Data on the segmental spread of analgesia from three independent studies of caudal extradural blocks in children with three different local anaesthetic agents were examined with multiple regression techniques to find the effects of age on dose requirements. All three studies confirmed the existence of a linear relationship between the spread of analgesia and age. ⋯ By injecting a mixture of a radio-opaque substance and 4% lignocaine it was shown by comparison of the radiological spread of the solution and the distribution of clinical analgesia that the latter always exceeded the former by four to six segments. This may indicate the occurrence of diffusion.