British journal of anaesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Anidoxime: a clinical trial of an oral analgesic agent.
The new oral analgesic drug anidoxime was compared with dihydrocodeine. There were no side-effects, and no significant differences between the effects of dihydrocodeine 50 mg, anidoxime 75 mg or anidoxime 100 mg.
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A simple method of adapting a pressure-cycled ventilator of the flow generator type to ventilate patients on a circle-absorber anaesthetic system is described. Standard lengths of corrugated black rubber tubing are placed between the ventilator and the circle-absorber is deadspace, replacing the reservoir bag. The performance of this modification was investigated and a functional volume for the tubing calculated. There was a simple relationship between the tidal volume, the length of tubing and the fresh gas flow required to avoid dilution of the anaesthetic gases by the driving gases.