The British journal of surgery
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This study evaluated the clinical characteristics, surgical procedures and prognosis of duodenal gastrointestinal stromal tumours (GISTs). ⋯ The prognosis of duodenal GISTs is similar to that of small intestinal GISTs.
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Review Meta Analysis
Meta-analysis of the effect of preoperative breast MRI on the surgical management of ductal carcinoma in situ.
MRI has been used increasingly in the diagnosis and management of women with invasive breast cancer. However, its usefulness in the preoperative assessment of ductal carcinoma in situ (DCIS) remains questionable. A meta-analysis was conducted to examine the effects of MRI on surgical treatment of DCIS by analysing studies comparing preoperative MRI with conventional preoperative assessment. ⋯ Preoperative MRI in women with DCIS is not associated with improvement in surgical outcomes.
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Surgeons provide patients with information before surgery, although standards of information are lacking and practice varies. The development and use of a 'core information set' as baseline information before surgery may improve understanding. A core set is a minimum set of information to use in all consultations before a specific procedure. This study developed a core information set for oesophageal cancer surgery. ⋯ This study has established a core information set for surgery for oesophageal cancer.
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Whether intraoperative cholangiography can prevent iatrogenic bile duct injury during cholecystectomy remains controversial. ⋯ Any proposed protective effect of intraoperative cholangiography was restricted to patients with (or a history of) acute cholecystitis.
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Randomized Controlled Trial Multicenter Study
Randomized clinical trial of mast cell inhibition in patients with a medium-sized abdominal aortic aneurysm.
Abdominal aortic aneurysm (AAA) is thought to develop as a result of inflammatory processes in the aortic wall. In particular, mast cells are believed to play a central role. The AORTA trial was undertaken to investigate whether the mast cell inhibitor, pemirolast, could retard the growth of medium-sized AAAs. In preclinical and clinical trials, pemirolast has been shown to inhibit antigen-induced allergic reactions. ⋯ NCT01354184 (https://www.clinicaltrials.gov).