The British journal of surgery
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Randomized Controlled Trial Multicenter Study
Randomized feasibility trial of replacing or discarding the nail plate after nail-bed repair in children.
Nail-bed injuries are the most common hand injury in children. Surgical dogma is to replace the nail plate after repairing the nail bed. Recent evidence suggests this might increase infection rates and returns to clinic. The aim of this feasibility trial was to inform the design and conduct of a definitive trial comparing replacing or discarding the nail plate after nail-bed repair. ⋯ Recruitment was rapid and nail-bed repair appeared to have low complication and infection rates in this pilot trial. The findings have led to revision of the definitive trial protocol, including the mode and timing of follow-up, and modification of the Zook classification.
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Multicenter Study
Short- and medium-term outcomes following primary ileocaecal resection for Crohn's disease in two specialist centres.
Despite improvements in medical therapy, the majority of patients with Crohn's disease still require surgery. The aim of this study was to report safety, and clinical and surgical recurrence rates, including predictors of recurrence, after ileocaecal resection for Crohn's disease. ⋯ Ileocaecal resection achieved durable medium-term remission, but smoking and resection margin positivity were risk factors for recurrence.