The British journal of surgery
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Randomized Controlled Trial Multicenter Study
Percutaneous tibial nerve stimulation in patients with severe low anterior resection syndrome: randomized clinical trial.
Treatment of low anterior resection syndrome (LARS) is challenging. Percutaneous tibial nerve stimulation (PTNS) can improve select bowel disorders. An RCT was conducted to assess the efficacy of PTNS compared with sham stimulation in patients with severe LARS. ⋯ PTNS has positive effects in some patients with major LARS, especially in those with faecal incontinence. Registration number: NCT02517853 (http://www.clinicaltrials.gov).
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Before the use of mechanical bowel preparation is either eliminated or subjected to a clinical trial, its scientific premise should be reconsidered, and consensus of its redesign discussed by a panel of experts including surgeons, infectious disease specialists, microbiome scientists, and clinical trialists.