The British journal of surgery
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Review Meta Analysis Comparative Study
Meta-analysis and meta-regression analysis of biomarkers for abdominal aortic aneurysm.
Many studies have investigated the systemic and local expression of biomarkers in patients with abdominal aortic aneurysm (AAA). The natural history of AAA varies between patients, and predictors of the presence and diameter of AAA have not been determined consistently. The aim of this study was to perform a systematic review, meta-analysis and meta-regression of studies comparing biomarkers in patients with and without AAA, with the aim of summarizing the association of identified markers with both AAA presence and size. ⋯ A wide variety of biomarkers are dysregulated in patients with AAA, but their clinical value is yet to be established. Future research should focus on the most relevant biomarkers of AAA, and how they could be used clinically.
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Review Meta Analysis Comparative Study
Meta-analysis of peak wall stress in ruptured, symptomatic and intact abdominal aortic aneurysms.
Abdominal aortic aneurysm (AAA) is an important cause of sudden death; however, there are currently incomplete means to predict the risk of AAA rupture. AAA peak wall stress (PWS) can be estimated using finite element analysis (FEA) methods from computed tomography (CT) scans. The question is whether AAA PWS can predict AAA rupture. The aim of this systematic review was to compare PWS in patients with ruptured and intact AAA. ⋯ This study suggests that PWS is greater in symptomatic or ruptured AAA than in asymptomatic intact AAA.
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Review Meta Analysis
Meta-analysis of operative mortality and complications in patients from minority ethnic groups.
Insight into the effects of ethnic disparities on patients' perioperative safety is necessary for the development of tailored improvement strategies. The aim of this study was to review the literature on safety differences between patients from minority ethnic groups and those from the ethnic majority undergoing surgery. ⋯ Patients from minority ethnic groups, in North America and elsewhere, have an increased risk of perioperative death and complications. More insight is needed into the causes of ethnic disparities to pursue safer perioperative care for patients of minority ethnicity.
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Randomized Controlled Trial Multicenter Study Comparative Study
Randomized clinical trial comparing self-gripping mesh with suture fixation of lightweight polypropylene mesh in open inguinal hernia repair.
Postoperative pain is an important adverse event following inguinal hernia repair. The aim of this trial was to compare postoperative pain within the first 3 months and 1 year after surgery in patients undergoing open mesh inguinal hernia repair using either a self-gripping lightweight polyester mesh or a polypropylene lightweight mesh fixed with sutures. ⋯ NCT00827944 (http://www.clinicaltrials.gov).
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Multicenter Study Observational Study
Incidence of and risk factors for incisional hernia after abdominal surgery.
Few larger studies have estimated the incidence of incisional hernia (IH) after abdominal surgery. ⋯ UMIN000004723 (University Hospital Medical Information Network, http://www.umin.ac.jp/ctr/index.htm).