Minerva anestesiologica
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Minerva anestesiologica · Jan 1995
Clinical Trial Controlled Clinical Trial[The use of dobutamine during the intraoperative period to prevent organ hypoperfusion in non-heart surgery. Administration modality and monitoring].
Dobutamine is strongly recommended in the treatment of critical intensive care patients in order to improve cardiac performance and peripheral perfusion. In non-cardiac surgery there are frequent cases of organ hypoperfusion that could be treated with dobutamine; the drug, however, is not advocated since it is difficult to control without invasive hemodynamic monitoring. This study analyzed the possibilities of using and controlling dobutamine in non-cardiac surgery. ⋯ The treated patients showed significantly higher blood pressure, exhaled CO2 and heart rate values, demonstrating that dobutamine infusion can be piloted on the basis of these monitoring parameters. The treated patients had 4% higher exhaled CO2 levels showing the close correlation between exhaled CO2 and the use of the inotrope. The overall results show that dobutamine is easy to use and readily piloted during anesthesia for non-cardiac surgery.
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Minerva anestesiologica · Jan 1995
Clinical TrialGastric intramucosal pH in trauma patients: an index for organ failure risk?
To assess if low gastric intramucosal pH (pHi), in the first 24 hours from trauma, is an early risk index for organ failure in severe trauma. ⋯ Our data suggest that low pHi during the first 24 hours from trauma seems to be a good predictor for the development of organ failure.
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Minerva anestesiologica · Dec 1994
Randomized Controlled Trial Comparative Study Clinical TrialA comparative study of conventional inhalation anaesthesia and total intravenous anaesthesia (TIVA) performed with midazolam and alfentanil.
To compare two anesthetic techniques, total intravenous anaesthesia performed with midazolam-alfentanil and classic inhalation anaesthesia. ⋯ Total intravenous anaesthesia (TIVA) seems simple, safe and feasible in hospitals of this country.
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Minerva anestesiologica · Dec 1994
[Survival in intensive care of patients with chronic obstructive bronchopneumopathy and acute respiratory failure undergoing mechanical ventilation. Retrospective study].
To collect valuable informations for the evaluation of the patients' clinical evolution and to perform a cost-effectiveness analysis on the utilization of resources in the management of patients with chronic obstructive pulmonary disease (COPD) undergoing mechanical ventilation (MV) for acute respiratory failure (ARF). ⋯ Our results demonstrate that hospital outcome in COPD patients with ARF requiring mechanical ventilation is quite good. Prolonged mechanical ventilation and--severity of underlying chronic respiratory disease do not affect significatively the prognosis. The high costs of the treatment of these patients are counterbalanced by a good efficiency of utilization of resources and appreciable clinical results.
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Minerva anestesiologica · Nov 1994
Randomized Controlled Trial Clinical Trial[Effects of betamethasone on neuromuscular blockade induced by vecuronium in continuous infusion].
The aim of the study was to determine a possible interaction between a corticosteroid (betamethasone) and vecuronium, a nondepolarizing muscle relaxant. The authors studied 20 patients, ASA I-II, aged 20-54, both sexes, scheduled for abdominal surgery. ⋯ The recovery rate of vecuronium after stopping infusion at 10% recovery was also evaluated. Corticosteroids may interact with non-depolarizing muscle relaxants both in prejunctional and postjunctional acetylcholine receptors by several mechanisms of action.