World Neurosurg
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This study sought to assess the results of current laboratory studies of olfactory ensheathing cell (OEC) transplantation for the treatment of central nervous system repair. ⋯ Although the exact mechanisms of action of OECs are not fully understood, it is clear that OECs have beneficial regenerative properties in laboratory studies, and the ease with which OECs can be harvested and cultured in animal models make clinical application a very reasonable prospect.
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One significant drawback during a cranial reoperation is the presence of meningocerebral adhesions. The appearance of connective tissue bridges between the inner surface of the dura and the pia-arachnoid is mostly related to dural closure and the condition in which the surgical field was left in the previous surgery. This study was done to determine the benefit of placing a thin-layer gelatin sponge of polypeptides subdurally to prevent meningocerebral adhesions. ⋯ This study proves that, during the dural closure, placing a thin layer of gelatin sponge in the subdural space is a safe and effective method for preventing meningocerebral adhesions.