World Neurosurg
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Meta Analysis
Post Traumatic Amnesia: A Systematic Review and Meta-Analysis. Proposal for a New Severity Classification.
Posttraumatic amnesia (PTA) duration is used to predict outcome after traumatic brain injury (TBI): however, no meta-analysis exists. ⋯ PTA duration was reliable in predicting outcome when <7 days, and especially when >42 days but was often unreliable between 7 and 42 days duration.
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Chondrosarcoma and chordoma are often grouped together because of their similar anatomic locations, clinical presentations, histopathological and radiological findings, and growth patterns. In the present study, we investigated the clinical and prognostic differences of chondrosarcomas and chordomas of the skull base and spine. ⋯ Chondrosarcomas and chordomas have divergent clinical manifestations and prognoses depending on the anatomic location.
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Review Meta Analysis
Growth Factor Gene-Modified Cells in Spinal Cord Injury Recovery: A Systematic Review.
Numerous preclinical studies have been performed in recent years on the effects of the administration of growth factor gene-modified cells in spinal cord injury (SCI). However, findings of these studies are contradictory. ⋯ The results showed that transplantation of growth factor gene- modified cells significantly improved locomotion in SCI animal models. However, there is a major concern regarding the safety of transplantation of genetically modified cells, in terms of overexpressing growth factors. Further studies are needed before any effort to perform a translational and clinical study.