World Neurosurg
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The bidirectional causal relationship between ischemic stroke(IS) and inflammatory bowel disease(IBD) remains unclear, prompting us to propose a bidirectional Mendelian randomization study to investigate this relationship further. ⋯ IBD and its subtypes were not found to be causally associated with the risk of IS, whereas IS was found to be causally associated with the risk of CD and UC. This suggests that the risks of CD and UC should be closely monitored in patients with IS.
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Different from typical primary central nervous system lymphoma (PCNSL), early-stage atypical PCNSL usually presents as patchy signal abnormalities without evident mass effect or significant contrast-enhancement and is prone to confusion with low-grade glioma (LGG). This study aims to develop an MRI-based radiomics model to differentiate early-stage atypical PCNSL from LGG. ⋯ The MRI-based radiomics model can accurately differentiate early-stage atypical PCNSL from LGG with similar radiological manifestations, allowing early-stage atypical PCNSL patients to receive timely and appropriate radiotherapy or chemotherapy while avoiding unnecessary surgical resection.
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Blister-like aneurysms represent a rare subtype characterized by a wide neck and dissecting appearance, predisposing them to perioperative rebleeding due to fragile walls. These aneurysms predominantly occur at non-branching sites of the internal carotid artery (ICA). Still, they may also manifest at atypical locations, including the anterior communicating artery (AComA), anterior cerebral artery, middle cerebral artery, posterior cerebral artery, and basilar artery.1 Treatment of blister-like aneurysms typically involves a combination of microsurgery and endovascular procedures, with no universally established optimal therapeutic approach. ⋯ During aneurysm surgery, an intraoperative rupture occurred that was controlled with a temporary clip. Sharp aneurysm dissection and then aneurysm clipping is made under the temporary clip. Six days after the operation, the patient was discharged home without any neurologic deficit.
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Cavernous malformations (CMs) are benign vascular lesions composed of clusters of dilated, thin-walled, blood-filled vessels. The prevalence of CMs in the general population ranges from 0.4%-0.9%, with the majority located in the brain, while spinal cord CMs represent rare subtypes. Spinal CMs are clinically significant due to their potential for symptomatic hemorrhage, leading to neurological deficits. Although rare, they have attracted increasing attention in the literature. Thereby both, intramedullary hemorrhage and spinal cord surgery bear the risk of injury. This case series reports functional outcomes following surgical and conservative treatment of spinal CMs. ⋯ Spinal CMs can be safely managed through surgical resection, with a relatively low morbidity rate and no reported mortality. Our results demonstrate that postoperative morbidity was predominantly characterized by sensory deficits, while motor deficits were less common.