J Gynecol Obst Bio R
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J Gynecol Obst Bio R · Nov 2009
Randomized Controlled Trial[Benefit of misoprostol for prevention of postpartum hemorrhage in cesarean section: a randomized controlled trial].
To assess the benefit of sublingual misoprostol in addition to standard oxytocin in the prevention of post-partum hemorrhage at caesarean section. ⋯ Sublingual misoprostol (in addition to oxytocin) is effective in prevention of post-partum hemorrhage at caesarean sections when compared to oxytocin alone, without major side-effects. Larger studies are needed to confirm our results.
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J Gynecol Obst Bio R · Jan 1991
Randomized Controlled Trial Comparative Study Clinical Trial[Use of etilefrin as local vasoconstrictor in lower gynecologic surgery ].
In this randomized prospective study the authors have compared the effectiveness and side-effects of two local vasoconstrictor agents, etilefrine (Effortil) and ornithine 8 vasopressin (Por 8) in vaginal gynaecological surgery. Thirty-three patients entered the trial and were divided into two groups: G1 (15 patients) received Effortil, and G2 (18 patients) received Por 8. The products, administered at random, were diluted in saline 40 ml and injected into the cervix through 6 points. ⋯ Diastolic BP was significantly higher in G2 than in G1 (P less than 0.002, Fisher test). Systolic BP was also elevated in that group (P less than 0.03, chi 2 test). Moderate reduction in heart rate was observed in both groups (P less than 0.3, Fischer test), but severe (48 beats/min) bradycardia was noted in one G2 patient.
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J Gynecol Obst Bio R · Jan 1983
Case Reports Randomized Controlled Trial Clinical Trial[Peridural analgesia during labor: comparative study of a fentanyl-marcaine combination and marcaine alone].
A randomised trial was carried out to evaluate the use of a mixture of fentanyl with marcaine in epidural analgesia. Two series of 30 patients each were studied: in the first only marcaine was given for the epidural and in the second marcaine and fentanyl mixed. Stronger and longer analgesia was obtained in the series where fentanyl was added showing that local anaesthetics can be potentiated by opiates. There was no significant difference in the two series as far as the cardiovascular, respiratory and blood gas measurements were concerned, either in the mother or in the fetus.