The Medical journal of Australia
-
Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease predominantly affecting women of childbearing age. New classification criteria for SLE have greater sensitivity and therefore improve the diagnostic certainty for some patients, especially those who may previously have been labelled as having undifferentiated symptoms. ⋯ The development of biological therapy lags behind that for other rheumatic diseases, with belimumab being the only targeted therapy approved by the Therapeutic Goods Administration. "Treat-to-target" concepts are changing trial design and clinical practice, with evidence-based definition of response criteria in the form of remission and low disease activity now on the horizon. While new therapies are awaited, research should also focus on optimising the use of current therapy and improving the quality of care of patients with SLE.
-
To determine the professional and personal factors associated with the intention to retire (ITR) by medical practitioners. ⋯ Intention to retire was determined by a mixture of professional and psychosocial characteristics. In particular, our results support the view that delaying retirement by doctors may be related to the primacy of work compared with other life roles. Our results may be used to develop educational programs that support the transition to and improve adjustment to retirement.