Minerva medica
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Meta Analysis
The clinical risk factors associated with postoperative bile leakage after hepatectomy: a meta-analysis.
The occurrence of bile leakage (BL) is one of the major contributors to the morbidity after hepatectomy. However, the clinical risk factors associated with postoperative BL remains controversial. This study aims to further assess the risk factors for BL. ⋯ Our meta-analysis reveals that previous liver or biliary surgery, anatomic resection, major hepatectomy, right anterior sectionectomy, left trisectionectomy, central bisectionectomy, blood transfusion, operative time, bile duct reconstruction, resection of segments 1, 2 and 5 involved had significant positive correlation with increased risk of BL, on the contrary, hepatic fibrosis/cirrhosis, left lateral sectionectomy had the opposite effect.
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Meta Analysis
Meta-analysis of diagnostic value of serum Carbohydrate antigen 199 in pancreatic cancer.
Carbohydrate antigen 199 (CA199) has been used as a new promising serum biomarker for the diagnosis of pancreatic cancer. But its utility was full of controversies. This study sought to determine the diagnosis value of serum CA199 in pancreatic cancer through enrolling all the related eligible studies. ⋯ The current analyses indicated that CA199 is a valuable marker in the diagnosis of pancreatic cancer.