Arch Intern Med
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Randomized Controlled Trial Multicenter Study Clinical Trial
A new pharmacological treatment for intermittent claudication: results of a randomized, multicenter trial.
Effective medication is limited for the relief of intermittent claudication, a common manifestation of arterial occlusive disease. Cilostazol is a potent inhibitor of platelet aggregation with vasodilation effects. ⋯ Compared with placebo, long-term use of cilostazol, 100 mg or 50 mg, twice a day significantly improves walking distances in patients with intermittent claudication.