Arch Intern Med
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Randomized Controlled Trial Multicenter Study
Effect of a traditional Mediterranean diet on lipoprotein oxidation: a randomized controlled trial.
Despite the richness in antioxidants of the Mediterranean diet, to our knowledge, no randomized controlled trials have assessed its effect on in vivo lipoprotein oxidation. ⋯ Individuals at high cardiovascular risk who improved their diet toward a TMD pattern showed significant reductions in cellular lipid levels and LDL oxidation. Results provide further evidence to recommend the TMD as a useful tool against risk factors for CHD. Trial Registration isrctn.org Identifier: ISRCTN35739639.
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Randomized Controlled Trial
Pharmacist medication assessments in a surgical preadmission clinic.
In the hospital setting, postoperative admission is a key vulnerable moment when patients are at increased risk of medication discrepancies. This study measures the reduction of medication discrepancies associated with a combined intervention of structured pharmacist medication history interviews with assessments in a surgical preadmission clinic and a postoperative medication order form. ⋯ A combined intervention of pharmacist medication assessments and a postoperative medication order form can reduce postoperative medication discrepancies related to home medications.
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Randomized Controlled Trial
Helping patients with type 2 diabetes mellitus make treatment decisions: statin choice randomized trial.
Poor quality of information transfer about the benefits and risks of statin drug use may result in patients not making informed decisions that they can act on in a timely fashion. ⋯ A decision aid enhanced decision making about statin drugs and may have favorably affected drug adherence.
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Randomized Controlled Trial
An intervention to improve secondary prevention of coronary heart disease.
Translating guidelines into clinical practice has proved to be quite difficult, even when the guidelines are well accepted and noncontroversial. Both computerized reminders and academic detailing have been effective in changing physician prescribing behavior. In this study, we sought to use these methods, mediated by clinical pharmacists, to improve adherence to the secondary prevention guidelines in hospitalized patients with myocardial infarction. ⋯ A computerized alert with pharmacist-mediated academic detailing is an effective means to increase adherence to secondary prevention guidelines for coronary heart disease.
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Randomized Controlled Trial
Massage therapy for osteoarthritis of the knee: a randomized controlled trial.
Massage therapy is an attractive treatment option for osteoarthritis (OA), but its efficacy is uncertain. We conducted a randomized, controlled trial of massage therapy for OA of the knee. ⋯ Massage therapy seems to be efficacious in the treatment of OA of the knee. Further study of cost effectiveness and duration of treatment effect is clearly warranted. .