J Postgrad Med
-
Meta Analysis
5HT3 antagonists for prophylaxis of postoperative nausea and vomiting in breast surgery: a meta-analysis.
Postoperative nausea and vomiting (PONV) are distressing adverse events following breast cancer surgery with an incidence of up to 80%. 5HT 3 antagonists are commonly employed as drugs of first choice for PONV although there is no clear evidence favoring one pharmacological approach over another. ⋯ 5HT 3 antagonists are superior to other pharmacological interventions for the prevention of PONV in patients undergoing breast surgery under general anesthesia.