Pak J Med Sci
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To determine the frequency of premature ejaculatory dysfunction in rheumatoid arthritis patients. ⋯ There is high prevalence of PED in RA, it needs proper evaluation, treatment and urgent research is needed to know more about it.
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Pakistan has high neonatal mortality rate and antibiotic utilization data in hospitalized term neonates from Pakistan is lacking. The study aimed to determine the pattern of hospital antibiotic use in term neonates using World Health Organization (WHO) Access, Watch, and Reserve classification (AWaRe). ⋯ High antibiotic prescription rate particularly from Watch-group is demonstrated in this study. There is high need of antimicrobial stewardship program in neonatal units.
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Pregnant women are the most susceptible group for Iodine deficiency disorder (IDD) whose neonate are at the risk of brain impairment, if they are iodine deficient in utero. The study was carried out to analyze the concerns and effects regarding iodized salt and IDD in women seeking antenatal care in Pakistan. ⋯ There is an immense need to address the present concerns of women seeking antenatal care by advocacy and health education on individual and at mass level regarding the use of iodized salt among women seeking antenatal care. Advocacy can be done by governmental initiatives, medical personnel and through mass media in all tertiary care hospitals of Pakistan.
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To screen Haemophilia-A patients for five known recurrent F8 gene variants and to analyze CA repeats in intron 13 of F8 gene in the mother and the affected child pairs. ⋯ The five known Haemophilia-A disease causing variants were found in 40% of the Pakistani Haemophilia-A patients. The five recurrent F8 gene variants and the CA repeats in intron 13 of F8 gene can provide a comprehensive basis for carrying out prenatal diagnosis and carrier screening in majority of the Pakistani Haemophilia-A families.
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To evaluate the clinical efficacy of neoadjuvant chemohormonal therapy (NCHT) combined with laparoscopic radical prostatectomy in high-risk prostate cancer (PCa). ⋯ NCHT combined with laparoscopic radical prostatectomy is a safe and effective treatment for high-risk PCa, which is worthy of promotion in clinical practice.