Neurology
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Randomized Controlled Trial Multicenter Study
Motor cortex stimulation does not improve dystonia secondary to a focal basal ganglia lesion.
To assess the efficacy of epidural motor cortex stimulation (MCS) on dystonia, spasticity, pain, and quality of life in patients with dystonia secondary to a focal basal ganglia (BG) lesion. ⋯ This study provides Class I evidence that bipolar epidural MCS with the anode placed over the motor representation of the most affected limb failed to improve any clinical feature in dystonia secondary to a focal BG lesion.
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Randomized Controlled Trial Multicenter Study
Cluster RCT of case management on patients' quality of life and caregiver strain in ALS.
To study the effect of case management on quality of life, caregiver strain, and perceived quality of care (QOC) in patients with amyotrophic lateral sclerosis (ALS) and their caregivers. ⋯ This study provides Class III evidence that case management in addition to multidisciplinary ALS care does not significantly improve health-related quality of life of patients with ALS.