Neurology
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Randomized Controlled Trial
Methylphenidate, cognition, and epilepsy: A double-blind, placebo-controlled, single-dose study.
To evaluate the potential efficacy of immediate-release methylphenidate (MPH) for treating cognitive deficits in epilepsy. ⋯ This study provides Class II evidence that single doses of MPH improve cognitive performance on some measures of attention and processing speed in patients with epilepsy and cognitive complaints.
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Randomized Controlled Trial Multicenter Study
Endovascular treatment improves cognition after stroke: A secondary analysis of REVASCAT trial.
To investigate the effect of endovascular treatment on cognitive function as a prespecified secondary analysis of the REVASCAT (Endovascular Revascularization With Solitaire Device Versus Best Medical Therapy in Anterior Circulation Stroke Within 8 Hours) trial. ⋯ This study provides Class I evidence that for patients with stroke from acute anterior circulation proximal arterial occlusion, thrombectomy improves performance on the TMT at 3 months.