BMC anesthesiology
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Multicenter Study Comparative Study
Immediate intravenous epinephrine versus early intravenous epinephrine for in-hospital cardiopulmonary arrest.
Intravenous epinephrine has been a key treatment in cardiopulmonary arrest since the early 1960s. The ideal timing for the first dose of epinephrinee is uncertain. We aimed to investigate the association of immediate epinephrine administration (within 1-min of recognition of cardiac arrest) with return of spontaneous circulation (ROSC) up to 24-h. ⋯ Immediate administration of epinephrine in conjunction with high-quality CPR is associated with higher rates of ROSC.