Brazilian journal of anesthesiology (Elsevier)
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There is not an ideal predictor of weaning from mechanical ventilation (MV). In a large meta-analysis, despite methodological limitations, respiratory rate (RR) was considered a promising predictor. The aim of this study was to evaluate RR as a predictor of weaning failure from MV. ⋯ RR was an effective predictor of weaning failure. The best cut-off point was RR > 24 rpm, which differed from those reported in the literature (35 and 38 rpm). Only 6% of patients were reintubated, but RR or other weaning criteria did not identify them.
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To assess the potential neurotoxic effects at the ultrastructural level of magnesium sulfate administered intrathecally as a single or multi-dose. ⋯ Based on electron microscopic examination, we found that intrathecal magnesium sulphate administration induced neurodegeneration.
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To assess the potential neurotoxic effects at the ultrastructural level of magnesium sulfate administered intrathecally as a single or multi-dose. ⋯ Based on electron microscopic examination, we found that intrathecal magnesium sulphate administration induced neurodegeneration.