Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
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Randomized Controlled Trial
Are N-of-1 trials an economically viable option to improve access to selected high cost medications? The Australian experience.
To explore the economic viability of N-of-1 trials for improving access to selected high cost medications in Australia. ⋯ The N-of-1 strategy offers a realistic and viable option for increasing access to selected high cost medications where the medications are used for the symptomatic treatment of chronic disease, have rapid onset of action, and clinical response is unpredictable without a trial.