European journal of heart failure
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Eur. J. Heart Fail. · Sep 2011
Randomized Controlled TrialShort-term opioids for breathlessness in stable chronic heart failure: a randomized controlled trial.
To assess the effect of oral opioids vs. placebo on breathlessness in patients with chronic heart failure (CHF). ⋯ We demonstrated no benefit over placebo for the relief of breathlessness with short-term low-dose oral opioids for CHF patients. Trial registered prior to the recruitment of the first participant with Current Controlled Trials (www.controlled-trials.com; Trial number ISRCTN 85268059).