Pain medicine : the official journal of the American Academy of Pain Medicine
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Multicenter Study Comparative Study
Exploring alternative approaches to routine outpatient pain screening.
To evaluate potential alternatives to the numeric rating scale (NRS) for routine pain screening. ⋯ Alternative single or combined pain screening strategies assessing pain-related bother may improve routine pain detection.
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To provide an overview of the role of voltage-gated sodium channels in pathophysiology of acquired and inherited pain states, and of recent developments that validate these channels as therapeutic targets for treating chronic pain. ⋯ These studies suggest that isoform-specific blockers of these channels or targeting of their modulators may provide novel approaches to treatment of pain.
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Case Reports
The development of an integrated treatment for veterans with comorbid chronic pain and posttraumatic stress disorder.
The purpose of this article is to describe the development of the first integrated treatment for Veterans with comorbid chronic pain and posttraumatic stress disorder (PTSD). ⋯ Participants appeared to benefit from receiving the integrated treatment for pain and PTSD. A randomized clinical trial is currently being conducted to evaluate the efficacy of this treatment approach.
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The objective of the study was to determine if there is dysregulated autonomic nervous system activity as manifested by depressed heart rate variability (HRV) among veterans of Operations Enduring and Iraqi Freedom (OEF/OIF). ⋯ These preliminary findings support the high prevalence of depressed HRV and P3 among veterans seen in a level II Polytrauma Center. The findings also suggest a possible synergistic effect of pain, PTSD, and mTBI on depressed HRV. The nature and implications of these relationships require additional research to elucidate.