Clinical & experimental ophthalmology
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Clin. Experiment. Ophthalmol. · Nov 2011
Comparative StudyGeldanamycin is effective in the treatment of herpes simplex virus epithelial keratitis in a rabbit model.
To evaluate the efficacy of geldanamycin eye drops against herpes simplex virus epithelial keratitis in a rabbit model. ⋯ Geldanamycin is a promising treatment option against herpes simplex virus type 1 epithelial keratitis. Geldanamycin (10 µg/mL) is better than acyclovir and geldanamycin (5 µg/mL) in the rabbit model. The optimal concentration of this drug in human is still to be determined.
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Clin. Experiment. Ophthalmol. · Nov 2011
Use of a novel haemostatic agent: ankaferd blood stopper in conjunctival incisions.
To investigate the haemostatic efficacy and histopathological effects of a new haemostatic agent, ankaferd blood stopper, in a rat conjunctival incision model. ⋯ Given the ease of use and lack of histopathological side-effects in the conjunctival incision model, ankaferd blood stopper is promising for use in ophthalmic surgery. Ankaferd blood stopper is a potent haemostatic agent. Its use in ophthalmic surgery should be investigated further in a larger cohort of patients and tested in clinical and experimental models.