The lancet oncology
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The lancet oncology · Jan 2025
The interplay between acute and late toxicity among patients receiving prostate radiotherapy: an individual patient data meta-analysis of six randomised trials.
The association between acute and late toxicity following prostate radiotherapy has not been well studied using data from multiple randomised clinical trials and fractionation schedules. We aimed to characterise the relationship between acute and late genitourinary and gastrointestinal toxicity among patients receiving conventionally fractionated or moderately hypofractionated prostate radiotherapy. ⋯ National Institutes of Health and US Department of Defense.
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The lancet oncology · Jan 2025
Comparative StudyColorectal cancer incidence trends in younger versus older adults: an analysis of population-based cancer registry data.
Previous studies have shown that colorectal cancer incidence is increasing among younger adults (aged <50 years) in multiple high-income western countries in contrast with stabilising or decreasing trends in incidence in older adults (aged ≥50 years). This study aimed to investigate contemporary colorectal cancer incidence trends in younger adults versus older adults. ⋯ Intramural Research Program of the American Cancer Society, Cancer Grand Challenges, and National Institutes of Health.