Journal of cosmetic dermatology
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Multicenter Study Comparative Study Clinical Trial
Effective noninvasive body contouring by using a combination of cryolipolysis, injection lipolysis, and shock waves.
Cryolipolysis combined with shockwave therapy has been previously shown to have synergistic effects in body contouring results. ⋯ Combination of cryolipolysis, radial shockwave, and injection lipolysis is a safe, well-tolerated treatment for reduction in subcutaneous fat.
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Randomized Controlled Trial Multicenter Study Comparative Study
A multi-center comparative efficacy and safety study of two different hyaluronic acid fillers for treatment of nasolabial folds in a Chinese population.
Nonsurgical injectable treatments, including hyaluronic acid (HA) fillers, are increasingly used in Asian patients. ⋯ Similar to Restylane, Restylane Lyft was effective and well tolerated for treatment of moderate to severe NLFs in this Chinese population.
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Multicenter Study Comparative Study
A prospective, comparative survey to investigate practitioners' satisfaction with a cohesive, polydensified-matrix(®) , hyaluronic acid-based filler gel with and without lidocaine for the treatment of facial wrinkles.
Lidocaine-containing dermal fillers may reduce procedural pain compared with lidocaine-free counterparts. ⋯ The lidocaine-containing dermal filler significantly reduced pain during and following treatment compared with the same preparation without lidocaine, without impact on administration, aesthetic outcome, or safety.
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Multicenter Study Observational Study
A prospective, open-label, multicenter, observational, postmarket study of the use of a 15 mg/mL hyaluronic acid dermal filler in the lips.
Hyaluronic acid (HA)-based injectable fillers three-dimensionally restore the natural contours of the lips and perioral area, thereby reducing some signs of aging lips. To evaluate the short-term aesthetic impact of treatment with the HA dermal filler Juvéderm(®) VOLBELLA(®) with Lidocaine, formulated utilizing VYCROSS(™) technology, for enhancement or correction of asymmetry of the lips, evaluated using a patient-centric approach. Sixty-two subjects were enrolled in this study, conducted at two sites in Germany. ⋯ After injection at first visit, 61.7% of subjects rated the look and feel of their lips as Extremely Natural or Very Natural, which increased to 75.0% and 93.0% of subjects with/without top-up treatment, respectively. The HA dermal filler was associated with minimal discomfort, bruising or swelling of the lips; almost two-thirds of subjects (62%) returned to social engagements on the same day. The high degree of subject satisfaction with aesthetic improvement in the lips, as well as the natural look and feel, indicates that this HA dermal filler represents an effective treatment option for patients requiring lip enhancement.
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Multicenter Study Comparative Study
Efficacy of hydroquinone-free skin-lightening cream for photoaging.
Hyperpigmentation and solar damage remains a difficult problem to treat with topical agents. ⋯ The SLC cream was well tolerated, in particular when comparing with exfoliating or peeling agent containing skin-lightening products. When used with a daily sunscreen, this study confirms that the SLC represents an alternative to hydroquinone, retinoids, and many other skin-lightening actives.