Articles: nerve-block.
-
Comparative Study
Differential nerve block by bupivacaine and 2-chloroprocaine. An experimental study.
The differential blocking effect of bupivacaine and 2-chloroprocaine was studied on isolated rabbit cervical sympathetic trunks (B and C fibres) and phrenic nerves (A fibres). The B fibres (myelinated, preganglionic) were more sensitive than C fibres (unmyelinated, postganglionic) to nerve block by bupivacaine and 2-chloroprocaine, as assessed by changes in action potential amplitude and latency. The blocking action of both bupivacaine and 2-chloroprocaine caused a decrease in amplitude in the B fibres approximately twice as great as that produced in the C fibres. ⋯ The average action potential amplitude of A fibres at that time was 78%. 2-Chloroprocaine 300 mumol litre-1 completely blocked B fibres in 4 min and C fibres in 15 min. At 15 min the average action potential amplitude of the A fibres was still approximately 35%. Although these two local anaesthetics differ structurally and physico-chemically, the rates of block of the different fibres were in the same order in vitro.
-
Randomized Controlled Trial Comparative Study Clinical Trial
Anaesthesia for surgical correction of fractured femoral neck. A comparison of three techniques.
Sixty patients with fractured neck of femur and scheduled for surgical correction were randomly allocated to receive one of three anaesthetic techniques: general anaesthesia; spinal analgesia; psoas compartment block. The patients in the local anaesthetic groups also received a light general anaesthetic. There was little difference in the pre-, intra- and postoperative events, and no difference in postoperative mortality.
-
Anasth Intensivther Notfallmed · Oct 1980
[Plasma concentrations of etidocaine after supraclavicular plexus block (author's transl)].
10 patients without concomitant hepatic or renal diseases were given brachial plexus block (Winnie) with etidocaine and the plasma concentrations of the drug were measured. The quantity of local anaesthetic was determined solely by the body weight and amounted to 4 mg/kg body weight. The mean peak concentration was 1.39 microgram/ml, the highest single concentration measured was 1.74 microgram/ml. Peak levels were reached within 40 minutes after administration of the local anaesthetic.
-
The obturator reflex is a frequent complication of the transurethral resection of bladder tumors, specially those localized at the side of bladder. The transurethral operation often must be interrupted, or changed into a transabdominal one, because of danger of bladder perforation or severe bleeding. In addition to spinal analgesia two techniques of obturator block are presented and their use is discussed.