Trending Articles
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Comparative Study
Prevention of systemic hyperlactatemia during splanchnic ischemia.
Arterial blood lactate increases as a result of poor tissue perfusion. In splanchnic hypoperfusion, increased hepatic lactate uptake may delay increases in arterial blood lactate. We hypothesized that during isolated reduction of mesenteric blood flow, maintaining systemic blood volume and flow by fluid resuscitation may prevent systemic hyperlactatemia and therefore mask splanchnic ischemia. ⋯ We conclude that the hepatic lactate uptake increases in response to hepatic lactate influx. Systemic hyperlactatemia and increased hepatic venous lactate concentrations are late consequences of mesenteric hypoperfusion if hypovolemia is prevented. The net exchange of lactate across the splanchnic region does not reflect hepato-portal lactate kinetics in this animal model of intestinal hypoperfusion.
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Controlled Clinical Trial
Reorganization of multi-muscle and joint withdrawal reflex during arm movements in post-stroke hemiparetic patients.
To investigate the behavior of the nociceptive withdrawal reflex (NWR) in the upper limb during reaching and grasping movements in post-stroke hemiparetic patients. ⋯ The central nervous system is unable to use the NWR substrate dynamically and flexibly in order to select the muscle synergies needed to govern the spatio-temporal interaction among joints.
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Ischemic heart disease is the leading cause of death globally. Coronary artery bypass graft (CABG) surgery and percutaneous coronary intervention (PCI) are the revascularization options for ischemic heart disease. However, the choice of the most appropriate revascularization modality is controversial in some patient subgroups. ⋯ Both CABG surgery and PCI are reasonable options for patients with advanced CAD. Patients with diabetes generally have better outcomes with CABG surgery than PCI. In cases of ULMD, multivessel CAD, or LVD, CABG surgery should be favored in patients with complex coronary lesions and anatomy and PCI in less complicated coronary disease or deemed a high surgical risk. A heart-team approach should evaluate coronary disease complexity, patient comorbidities, patient preferences, and local expertise.
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J Comput Assist Tomogr · May 2014
Comparative StudyHigh spatial resolution, respiratory-gated, t1-weighted magnetic resonance imaging of the liver and the biliary tract during the hepatobiliary phase of gadoxetic Acid-enhanced magnetic resonance imaging.
The aim of this study was to demonstrate the clinical feasibility of a recently developed navigator-gated, 3-dimensional gradient echo (3D-GRE) sequence for high-resolution, T1-weighted imaging (HR-T1WI) during the hepatobiliary phase (HBP) of gadoxetic acid-enhanced liver magnetic resonance imaging (MRI). ⋯ T1-weighted gated-VIBE showed technical feasibility for HR-T1WI during HBP imaging of gadoxetic acid-enhanced MRI.