• Rev Esp Anestesiol Reanim · Apr 2013

    Case Reports

    Sugammadex reversal of rocuronium-induced neuromuscular blockade in two types of neuromuscular disorders: Myotonic dystrophy and spinal muscular atrophy.

    • P A Stewart, S Phillips, and H D De Boer.
    • Department of Anesthesia, Sydney Adventist Hospital, Wahroonga, NSW, Australia.
    • Rev Esp Anestesiol Reanim. 2013 Apr 1; 60 (4): 226-9.

    AbstractNeuromuscular disorders like myotonic dystrophy (dystrophia myotonica or Steinert's disease) and spinal muscular atrophy are associated with perioperative complications related to muscle weakness. These patients have an increased sensitivity to non-depolarising neuromuscular blocking agents, which can lead to postoperative residual curarization (PORC) and its associated respiratory complications. Adequate reversal of neuromuscular blockade is essential to prevent this. Sugammadex is the first selective relaxant binding agent and it reverses rocuronium- and vecuronium-induced neuromuscular block. Two cases are reported in which the patients received sugammadex to reverse a rocuronium-induced neuromuscular block. Reversal of the rocuronium-induced neuromuscular block (NMB) in both cases was fast, effective and without recurarization, and no safety concerns were observed.Copyright © 2012 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Published by Elsevier España. All rights reserved.

      Pubmed     Full text  

      Add institutional full text...

    Notes

     
    Do you have a pearl, summary or comment to save or share?
    250 characters remaining
    help        
    You can also include formatting and links in your notes
    • Simple formatting can be added to notes, such as _italic_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)

    hide…

Want more great medical articles?

Keep up to date with a free trial of metajournal, personalized for your practice.
845,020 articles already indexed!

We guarantee your privacy. Your email address will not be shared.